The annual UCSF Medical Center Clinical InQuERI Nursing Research Conference provides nurses with a full day of learning and engagement regarding a variety of approaches to clinical inquiry, highlighting projects at UCSF. The conference is intended to stimulate thought and discussion by showcasing the everyday impact these clinical inquiry activities can have at the bedside and beyond. Clinical inquiry is the ongoing process of questioning and evaluating practice and providing informed practice based on the best available data. It includes innovation via research and experiential learning, quality improvement, and evidence-based practice. Program highlights include keynote speakers offering an engaging presentation about an aspect of inquiry, Evidence based practice fellows projects, Joanna Briggs Institute Clinical Fellows projects, poster sessions, and breakout mini sessions.